to NR2CON and Bringing Neural Repair to
UDAAN Project for CP,
UDAAN HBOT-BASED MULTIMODE THERAPY FOR CP
The UDAAN HBOT-Based Multi-mode Long-Term Observational
Study for CP is an ongoing observational study.
We gave Standard Therapy on a one-to-one basis to twenty
young CP children, and followed them up for six months.
Since June 2001, another matching group of CP children was
given one session a day of HBOT at a pressure of 1.75 ATA, with 100% Oxygen for
60 minutes for 40 session at the beginning of therapy, followed in the fifth
month by 60 sessions of CP-Specific Acupuncture and 90 days of a standardized
purified preparation of a Unani herbal brain-restorative health supplement.
By July 2004, current worldwide opinion suggested that 1.5
ATA pressure could deliver better results, and we changed our protocol
About the same time, evidence, especially from increasing
acceptance of Pierre’s HBOT in CP study published in The Lancet of 2001
suggested that the brain could improve equally well with only 1.3 ATA pressure
given using ambient air only. Accordingly, by late 2005, we started a fresh arm
using the low pressure ambient air Hyperbaric Air study.
All the arms are part of our ongoing long term study, to see
what effect these various pressure and oxygen level models have on young Indian
Children with CP.
Interim analysis of results shows that only Standard Therapy achieves good improvement in small CP children
after 6 months.
All three HBOT groups achieved an improvement rate on GMFM scores that were highly statistically
significant better than that achieved by Standard Therapy only.
The 1.5 ATA HBOT and 1.3 ATA Hyperbaric Air groups were
slightly better than the 1.75 ATA group with little difference between the
Results with Special Education and Speech Therapy
evaluations followed a similar trend.
Detailed analytical data will be presented.
HBOT based regimens offer a faster and significantly better
improvement in the quality of life of CP children if started young, with many of
the children showing rapid progression in mobility, communication and cognitive
The improvement in Cognitive levels was something that could
only have been the result of the UDAAN Multimode Approach, as that is one
parameter that is Therapy independent to a large extent.